Naltrexone originated as an opioid antagonist and was prescribed to block opioid effects and relieve opioid-induced constipation. When administered in low-dose form, this medication may help patients suffering from chronic pain, metabolic issues, and certain weight loss conditions. This drug has anti-inflammatory properties which can alleviate pain and reduce bodily inflammation leading to weight gain.

Low-dose naltrexone (LDN), marketed under the brand name Contrave, may succeed where other weight loss methods have failed. This FDA-approved drug can help patients maintain their weight levels and promotes overall health and wellness. During an initial consultation, Dr. Edward Jacobson can answer any questions you may have about Naltrexone (LDN) and weight loss.

LDN and Weight Loss

LDN does not help all patients lose weight. Exactly why some patients respond to this drug and others do not is still not easily discernable, but research shows that LDN can significantly lower insulin resistance, which is a frequent cause of weight gain. This is especially true if a person also has hypothyroidism and cannot produce a sufficient amount of thyroid hormones.

Naltrexone promotes weight loss by moderating the body’s appetite. LDN sends signals to the brain which indicate that the body is not hungry, so the desire to overeat dissipates. Eventually, changes in a person’s dietary behavior become habitual, which also helps keep the weight off.

Weight loss does not occur quickly with Naltrexone, but those who stick to the regimen may enjoy long-term benefits. However, if a patient does not experience weight loss within the first few months, LDN is unlikely to work for them at all.

In addition to Naltrexone, each patient receives a custom-tailored diet and exercise plan to catalyze and maintain weight loss. Patients may also receive recommendations for individual hormone and supplement therapy based on their individual needs.

It is advised that most patients take LDN at night since it can also improve sleep irregularities. Since LDN is best taken with food, patients in Rhode Island can discuss which foods are suitable for them with a skilled doctor.

Side Effects and Contraindications

LDN therapy may cause side effects, some of which can be serious. Notify a doctor immediately if any of the following symptoms occur after taking Naltrexone:

Some lesser side effects include dry mouth, headache, insomnia, nausea, constipation, and diarrhea. However, careful monitoring and dosage adjustments may relieve these symptoms.

Additionally, some people should not take Naltrexone under any circumstances. Those diagnosed with the following conditions are not candidates for LDN therapy:

  • Uncontrolled high blood pressure
  • Diabetes
  • Liver or kidney diseases
  • Cardiovascular issues
  • Seizures
  • Eating disorders

Heavy alcohol users and those taking medications containing bupropion, such as Wellbutrin, are not Naltrexone candidates. Anyone using opioids or taking medication to block the effects thereof should not receive LDN. Furthermore, those who have undergone an organ transplant should refrain from using this drug.

Pregnant women or those planning to become pregnant should also not take Naltrexone. Finally, this drug is not available for people under age 18.

Consult a Physician about Naltrexone (LDN) and Weight Loss

If you have questions about your candidacy for naltrexone (LDN) and weight loss therapy, Dr. Jacobson may be able to help. Tell an experienced doctor at our Greenwich office about all the medications and supplements you take, whether prescription or over-the-counter, so we can determine whether this treatment option is right for you.